ANA (Antinuclear Antibody) Test: 5 Pearls Segment

Core IM

Despite knowledge regarding the lack of specificity of ANA positivity, there remain gaps in understanding and practice patterns related to ANA referrals and interpreting ANA positivity.  Given rates of ANA positivity up to 15-20% in the otherwise healthy population, recognizing symptoms and laboratory findings that raise concern for autoimmune disease and warrant ANA testing is critical to understand.   This episode will explore the significance of a positive ANA, including how to interpret ANA titers and patterns.  The Core IM team will review signs, symptoms, laboratory testing and physical exam findings that are concerning for autoimmune disease for which an ANA should be sent. Finally, the episode will review conditions associated with a positive ANA that are not rheumatologic including infections, malignancies and other non-rheumatic autoimmune diseases.  You’re invited to join the team for ANA (Antinuclear Antibody) Test: 5 Pearls Segment.

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Core IM