5 Pearls on Guideline-Directed Medical Therapy Part 1

Core IM

With the recent publication of new clinical trials in the management of heart failure, practice guidelines are rapidly changing. Although beta-blockers and MRA were already well established in reducing morbidity and mortality, newer studies have shown that ARNI are superior to ACE inhibitors (PARADIGM 2014, PIONEER-HF 2019). SGLT2 inhibitors have also proven to decrease heart failure hospitalization and cardiovascular deaths (DAPA-HF 2019, EMPEROR-Reduced 2020). This has led to the publication of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.  Join the Core IM team as they explore the importance for learners to be updated with the most recent guideline-directed medical therapy recommendations for heart failure.

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